Recommended Books on Gingivitis
Gingivitis - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so.
Immunization with Porphyromonas Gingivalis Cysteine Protease: Effects on Experimental Gingivitis and Ligature-Induced Periodontitis in Macaca Fascicularis This is a AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH report procured by the Pentagon and made available for public release. It has been reproduced in the best form available to the Pentagon. It is not spiral-bound, but rather assembled with Velobinding in a soft, white linen cover. The Storming Media report number is A383323. The abstract provided by the Pentagon follows: Targeting specific bacterial virulence factors such as proteases for immunization may hold the key to limiting or preventing loss of attachment and alveolar bone in periodontal disease. This study was undertaken to examine the clinical, microbiological and immunological responses following active immunization with a purified 120 kDa Porphyromonas gingivitis cysteine protease (porphypain-2) in the nonhuman primate (Nhp) Macaca fascicularis (cynomolgus monkey). 4 Nhp were immunized with 100ug of porphypain-2 antigen at baseline, 2 and 4 weeks. A 'non-immunized' control group of 4 Nhp received placebo injections. The animals were subjected to a 4 week experimental gingivitis phase initiated by soft diet, followed by a 13 week ligature-induced periodontitis phase. Mandibular left 'test' teeth (3-5, 3-6, 3-7) in each animal received silk ligatures to initiate periodontitis, with mandibular right teeth (4-5, 4-6, 4-7) in each animal serving as a non-ligated intra-animal control. Clinical, radiographic, microbiologic and immunologic data were gathered and analyzed using the student t-test and nonparametric rank analyses. An ELISA demonstrated that immunization elicited an elevated and specific IgG response to both whole cell P. gingivalis (36-fold) and to porphypain-2 (194- fold). This antibody response in immunized Nhp remained significantly elevated versus baseline (P < 0.0001) and the control group (P < 0.00001) throughout the study.
The Official Patient's Sourcebook on Gingivitis This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to gingivitis (also denture sore mouth; mild gum disease; mild gum inflammation), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on gingivitis. Given patients' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms.
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